Ageing is a universal phenomenon that has captivated human curiosity for centuries. As scientific research unravels the mysteries of the ageing process, one area is gaining prominence: epigenetics. Ageing and epigenetics are linked through molecular changes that control gene behaviour without altering the DNA code. Epigenetic modifications influence which genes are activated or silenced. Thus, these changes impact cellular functions and the ageing process. In this article, we’re looking at epigenetics’ meaning and how it affects the natural progression of ageing. Tag along as we explore this connection, providing insights into the ageing process and epigenetic modifications at the cellular level. Epigenetics: What Is It? Epigenetics is recognised as a relatively new and rapidly growing field within biology and medicine. It primarily deals with heritable changes in gene activity that do not involve alterations to the underlying DNA sequence. It focuses on modifications to DNA and its associated proteins. Epigenetics governs gene expression with the help of regulatory mechanisms, including DNA methylation, histone modification, and non-coding RNAs. These mechanisms regulate when and how genes are activated, acting like molecular switches that turn genes on or off. These changes are crucial in development, health, and the ageing process. The Ageing Process The human body is designed to function for a limited number of years and declines gradually with age. Most people think of ageing in terms of chronological age, i.e. the length of time you have lived. However, biological age looks at a person’s overall well-being and physiological state, taking into account alterations at the cellular level. In the scientific context, ageing is a non-genetic process that affects our entire body. It is the gradual decline of biological systems, leading to reduced resilience and an increased risk of age-related issues. Epigenetic Changes with Ageing A myriad of factors influence the multifaceted phenomenon of ageing. These range from inherent genetic characteristics to external elements like environmental exposures and lifestyle decisions. At the cellular level, ageing is accompanied by a complex interplay of genetic and epigenetic alterations. Epigenetic modifications, unlike genetic changes that involve alterations to the underlying DNA sequence, affect gene expression without changing the actual genetic code. These changes are not only dynamic but also possess inheritability, indicating their ability to pass down to subsequent generations. How Do Epigenetic Changes Impact Cellular Function? Epigenetic changes have consequences that ripple through cellular function. The impact of these changes extends beyond individual cells to influence the broader processes of development, health, and ageing. Epigenetic modifications serve as a regulatory mechanism. These control gene expression patterns that play a crucial role in determining cellular functions. As individuals age, the cumulative effects of these epigenetic changes contribute to the ageing process and age-related diseases. Genes crucial for maintaining cellular health may become silenced or overactive, leading to imbalances. As epigenetic regulation becomes disrupted, this contributes to the wear and tear associated with ageing cells. The Role of Environmental Factors Both genes and lifestyle play roles in ageing. Your genes set the stage, but your choices of what you eat, your activity level, and your environment seriously impact how you age. Epigenetic changes, in particular, are modifications to the DNA that result from external influences. External factors like lifestyle, environment, and diseases also speed up ageing beyond what’s normal for a certain age. Thus, it’s a mix of nature and nurture. Intriguingly, studies indicate that individuals exposed to certain environmental factors may experience accelerated ageing at the molecular level. Conversely, adopting a healthy lifestyle can positively impact our epigenetic landscape, potentially slowing down the ageing process. Defy Epigenetic Ageing with NADIOL! NAD+ (Nicotinamide Adenine Dinucleotide) plays a pivotal role in epigenetic regulation. It influences gene expression patterns that contribute to the ageing process. With age, cellular NAD+ levels decline, impacting energy production and cellular repair mechanisms. However, NADIOL’s PURE NMN and NR supplements have the power to boost NAD+ levels, potentially reversing age-related declines. Supplementing with these NAD+ precursor supplements can promote longevity and influence epigenetic processes associated with ageing. To support a more youthful epigenetic profile and healthier ageing at the molecular level, check out these NADIOL supplements. PURE NMN Powder PURE NR Supplement Decoding Epigenetics and Longevity Delving into the connection between environmental factors and epigenetics, it’s apparent that our choices made today shape our cellular destiny tomorrow. So, turn back your epigenetic clock with NADIOL’s NMN and NR supplements. Elevate your NAD+ levels today to defy ageing and maintain harmony within your body for a longer, healthier life.